Buy GW-501516 Powder (Cardarine) Online | High-Purity PPARδ Agonist Research Chemical
Introduction to Buy GW-501516 Powder (Cardarine)
Buy GW-501516 Powder, widely recognized by the research designations Cardarine or Endurobol, is a potent, synthetic, and highly specific agonist of the Peroxisome Proliferator-Activated Receptor delta (PPARδ). While frequently categorized alongside SARMs in the research supply market, it is crucial to note that GW-501516 is fundamentally distinct; it is a metabolic modulator with no androgenic activity.
Originally developed in the 1990s through a collaborative effort between GlaxoSmithKline (GSK) and Ligand Pharmaceuticals to treat dyslipidemia and metabolic syndrome, GW-501516 operates by activating the PPARδ pathway. This activation fundamentally alters the body’s energy metabolism, shifting it toward fatty acid oxidation and enhancing mitochondrial biogenesis. Supplied as a raw, stable powder, GW-501516 offers exceptional versatility for laboratories requiring custom volumetric dosing, in-vitro assay preparation, and advanced metabolic research calibration. Note: This product is strictly intended for in-vitro research and analytical purposes only.
Key Features and Benefits – Buy GW-501516 Powder (Cardarine)
- PPARδ Pathway Modeling: GW-501516 provides researchers with a highly specific tool to study the PPARδ pathway, mapping its role in lipid metabolism, glucose homeostasis, and mitochondrial respiration.
- Metabolic Modulation Research: Ideal for investigating the upregulation of fatty acid oxidation and energy expenditure in skeletal muscle and hepatocyte cell cultures without engaging androgen receptors.
- Raw Powder Versatility: Supplied as a pure, raw powder, this format allows researchers to create precise, custom-concentration volumetric solutions for in-vitro assays, eliminating the variables and excipients of pre-mixed liquids or capsules.
- Enhanced Stability: The raw powdered form of Cardarine is highly stable when stored correctly, ensuring long-term viability for ongoing longitudinal studies and archival reference standards without solvent breakdown over time.
Product Specifications
- Chemical Name: [2-methyl-4-((4-methyl-2-(4-trifluoromethylphenyl)-1,3-thiazol-5-yl)methylsulfanyl)phenoxy]-acetic acid
- Common Designation: GW-501516 / Cardarine / Endurobol / GSK-516
- CAS Number: 317318-70-0
- Class: PPARδ Agonist / Metabolic Modulator / Research Chemical
- Form: Raw Synthetic Powder
- Purity: ≥ 98% (Verified by Independent Third-Party Testing)
- Appearance: White to off-white fine crystalline powder
- Storage Requirements: Store in a cool, dry, dark environment (ideally -20°C for long-term archival). Keep container tightly sealed under inert gas to prevent moisture absorption and degradation.
- Solubility: Soluble in DMSO, ethanol, and PEG; practically insoluble in water.
Applications and Usage
GW-501516 Powder is exclusively designated for in-vitro (outside a living organism) research and analytical applications. Common laboratory applications include:
- PPARδ Gene Expression Assays: Investigating the mechanism by which GW-501516 alters the transcription of genes responsible for lipid metabolism and mitochondrial biogenesis in cell culture models.
- Metabolic and Mitochondrial Studies: Analyzing the effect of PPARδ agonism on oxidative phosphorylation, fatty acid oxidation, and energy expenditure in skeletal muscle and liver cells.
- Dyslipidemia Research: Modeling the effects of PPARδ activation on cholesterol transport and lipid profiling in hepatocyte cultures.
- Forensic and Analytical Standard: Utilizing GW-501516 as a certified reference material (CRM) for LC/MS, GC/MS, and HPLC spectroscopy to validate analytical instruments and detect metabolic modulators in biological matrices.
Disclaimer: This product is not for human or veterinary consumption. It must only be handled in controlled laboratory environments by qualified professionals.
Purity and Testing
We guarantee a purity level of ≥ 98% for our GW-501516 Powder. Every batch undergoes rigorous, independent third-party testing to verify chemical identity, absolute purity, and the absence of dangerous residual solvents, heavy metals, or unreacted precursors. We ensure our Cardarine is free from impurities commonly found in inferior synthetics. Certificates of Analysis (CoA) and Safety Data Sheets (SDS) are provided upon request, ensuring complete traceability and compliance for your research institution.
Safety and Handling
As a potent investigational metabolic modulator with identified toxicological risks in animal models, GW-501516 Powder must be handled with strict laboratory safety protocols:
- Personal Protective Equipment (PPE): Always wear appropriately sized nitrile gloves, chemical-resistant safety goggles, and an N95 or P100 particulate respirator when weighing or transferring the powder.
- Ventilation: Handling must only occur within a certified chemical fume hood to prevent the inhalation of aerosolized particles.
- Accidental Exposure: In the event of skin contact, wash the area thoroughly with soap and water. For eye contact, flush with copious amounts of water for at least 15 minutes.
- Hygiene: Remove contaminated clothing immediately and wash hands thoroughly after handling, even when PPE is utilized.
Global Shipping and Discreet Delivery
- Global Reach: We ship GW-501516 Powder internationally, in strict compliance with international shipping regulations.
- Discreet Packaging: All orders are dispatched in unmarked, tamper-evident, and odor-proof packaging. The outer packaging does not indicate the nature of the contents.
- Rapid Processing: Orders are processed and shipped within 24 hours of cleared payment. We offer standard and express courier options with full end-to-end tracking.
- Secure Handling: Powders are double-sealed in moisture-barrier bags and placed within sturdy outer containers to prevent damage during transit.
Why Choose Us To Buy GW-501516 Powder (Cardarine)?
- Uncompromising Quality: We work directly with top-tier chemical synthesis laboratories and verify every batch in-house and via third-party labs before it reaches you.
- Total Transparency: We provide full analytical data. What is on the label is exactly what is in the bag—no fillers, no impurities, no compromises.
- Expert Customer Support: Our support team understands the nuances of research chemicals and is ready to assist with CoA requests, shipping inquiries, and technical questions.
- Secure Transactions: We utilize SSL encryption and accept secure, discreet payment methods, including major cryptocurrencies (Bitcoin, Monero, Ethereum) and secure bank transfers.
Legal and Safety Compliance
GW-501516 (Cardarine) Powder is sold strictly as a research chemical and is not approved by the FDA, EMA, or any equivalent regulatory body for human or veterinary use. It is an investigational compound.
It is the sole responsibility of the purchaser to ensure that the acquisition, possession, and use of GW-501516 comply with all local, state, national, and international laws. Warning: Clinical development of GW-501516 was permanently halted after animal models demonstrated it caused rapid development of multiple types of cancer at high doses. It is highly carcinogenic in animal models. Furthermore, it is prohibited by the World Anti-Doping Agency (WADA) and is banned in all competitive sports. We do not ship to regions where this compound is explicitly prohibited for purchase. By purchasing from us, you affirm that you are a qualified researcher or institutional buyer over the age of 18, and you assume all legal liability for the product upon delivery.
Frequently Asked Questions (FAQ)
Q1: Is GW-501516 (Cardarine) a SARM?
A: No. While frequently grouped with SARMs in the research market, GW-501516 is a PPARδ agonist (a metabolic modulator). It does not bind to androgen receptors, nor does it exert anabolic effects on muscle tissue. Its primary mechanism involves activating the PPARδ pathway, which regulates genes involved in lipid and glucose metabolism.
Q2: Why was GW-501516 discontinued in clinical trials?
A: Development was halted by GlaxoSmithKline after long-term, high-dose animal studies revealed that GW-501516 caused rapid and severe development of malignant tumors in multiple organs (including the liver, stomach, and bladder). This carcinogenic profile is a critical focus in toxicological and PPARδ research today.
Q3: Why buy GW-501516 in raw powder form?
A: Raw powder offers maximum flexibility for laboratory researchers. It allows for the creation of highly specific, custom-concentration volumetric solutions tailored to unique in-vitro assay requirements. It also guarantees no degradation or contamination from liquid suspension agents, and allows for long-term stable storage.
Q4: Can GW-501516 Powder be consumed by humans?
A: Absolutely not. GW-501516 is an investigational research chemical with documented carcinogenic risks in animal models. It is strictly for in-vitro laboratory and analytical research. Human ingestion is strictly prohibited and highly dangerous.
Q5: Do you provide a Certificate of Analysis (CoA)?
A: Yes. We provide a comprehensive CoA—including HPLC, GC/MS, and NMR data—for every batch we sell. This guarantees the identity, purity, and safety of the compound for your analytical research.
Q6: Is it legal to buy GW-501516 in my country?
A: Legality varies drastically. While legal for legitimate research in many parts of the world, it is heavily regulated in some countries. It is banned by WADA for sports. We cannot provide legal advice. It is your responsibility to research your local laws before placing an order.
Q7: How should I store GW-501516 Powder for long-term research?
A: For maximum longevity, store GW-501516 powder in an airtight, amber glass vial under an inert gas (like Argon) in a freezer set to -20°C. Keep away from direct sunlight, heat, and moisture. When properly stored, the raw powder remains highly stable for years.




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